While going through my email folders I noticed an email chain about disabling your USB controller to avoid avoid the well known IRQ sharing situation. This has been extensively described in KB Article 1003710. In short: IRQ Sharing limits interrupts to a single CPU. Normally this isn’t a problem but the Service Console is locked to CPU 0 which thus could lead to a bottleneck when using high interrupt devices.
With vSphere this isn’t the case anymore. As of vSphere the VMkernel is the proud owner of for instance your USB controller. So remember when you are doing an implementation or creating a design there’s no need to disable the USB controller anymore!