This week I received a question about Storage DRS. The question was if it was possible to have a VM with multiple disks in different datastore clusters? It’s not uncommon to have set ups like these so I figured it would be smart to document it. The answer is yes that is supported. You can create a virtual machine with a system disk on a raid-5 backed datastore cluster and a data disk on a raid-10 backed datastore cluster. If Storage DRS sees the need to migrate either of the disks to a different datastore it will make the recommendation to do so.