There are a couple of great articles out there which are definitely worth reading: Colin McNamara – Cisco releases Nexus 1000v virtual switch for VMware Scott Lowe – BC2621: Fault-Tolerant VMs in VI: Operations and Best Practices (live blogging) Scott Lowe – TA2668: VMware ESX Architectural Directions (live blogging) Rich Brambley – TA3807: VirtualCenter Directions (live blogging)

My colleague Rene Jorissen just posted a config example for a port-channel and trunk configuration for VMware. So for those interested in networking check it out.